منابع مشابه
Restoring sight in blind cavefish
which sleep uni-hemispherically or bi-hemispherically depending on the context [3], captive cetaceans almost never sleep bilaterally [ ,8,9] even when they are motionless [ 0]. Unraveling how marine mammals manage the inherent tradeoff [3] between wakefulness and sleep will require the development of procedures for observing eye closure and other physiological variables, including EEG, in free-...
متن کاملWhy cavefish are blind.
Some fish exist as eyed, surface-dwelling and eyeless, cave-dwelling forms. The developmental processes that cause eye degeneration in different populations of Astyanax cavefish are similar. Although small optic primordia start to form, apoptosis of lens cells triggers developmental arrest and degeneration of the eyes. Degeneration has been linked to reduced expression of the transcription fact...
متن کاملLoss of Schooling Behavior in Cavefish through Sight-Dependent and Sight-Independent Mechanisms
BACKGROUND Surface populations of Astyanax mexicanus, living in rivers like their common ancestors, school, while several, independently derived cave populations of the same species have lost schooling behavior. RESULTS We quantify schooling behavior in individual A. mexicanus and identify quantitative trait loci (QTL) for this trait. We find that the evolutionary modulation of schooling has ...
متن کاملRestoring eye size in Astyanax mexicanus blind cavefish embryos through modulation of the Shh and Fgf8 forebrain organising centres.
The cavefish morph of the Mexican tetra (Astyanax mexicanus) is blind at adult stage, although an eye that includes a retina and a lens develops during embryogenesis. There are, however, two major defects in cavefish eye development. One is lens apoptosis, a phenomenon that is indirectly linked to the expansion of ventral midline sonic hedgehog (Shh) expression during gastrulation and that indu...
متن کاملGenome Editing Using TALENs in Blind Mexican Cavefish, Astyanax mexicanus
Astyanax mexicanus, a teleost fish that exists in a river-dwelling surface form and multiple cave-dwelling forms, is an excellent system for studying the genetic basis of evolution. Cavefish populations, which independently evolved from surface fish ancestors multiple times, have evolved a number of morphological and behavioral traits. Quantitative trait loci (QTL) analyses have been performed ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Biology
سال: 2008
ISSN: 0960-9822
DOI: 10.1016/j.cub.2007.11.023